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Is the 25-Year-Old Frontal Lobe Development Idea a Myth?
The current research suggests that it keeps developing until around 30, but a lot of the development is done by around 25. This isn't a magic number, this kind of research deals with averages rather than saying EVERYONE's brain is developed by 25.
The current research suggests that it keeps developing until around 30, but a lot of the development is done by around 25. This isn’t a magic number, this kind of research deals with averages rather than saying EVERYONE’s brain is developed by 25.
See lessHow are depression, anxiety, bipolar quantified in mice models?
iirc the most popular test for depression is the forced swim test [https://en.wikipedia.org/wiki/Behavioural_despair_test](https://en.wikipedia.org/wiki/Behavioural_despair_test) IMO thoses tests are mostly bad and unfit to compare to a human being happiness. Some proxy metrics though like locomotioRead more
iirc the most popular test for depression is the forced swim test
[https://en.wikipedia.org/wiki/Behavioural_despair_test](https://en.wikipedia.org/wiki/Behavioural_despair_test)
IMO thoses tests are mostly bad and unfit to compare to a human being happiness.
Some proxy metrics though like locomotion and conditioned place preference can be an indicator of the potency of a stimulant or activating antidepressant.
some nootropic/nocitropic tests exist too.
[https://en.wikipedia.org/wiki/Barnes_maze](https://en.wikipedia.org/wiki/Barnes_maze)
best is to directly measure neurotransmitters levels and extrapolate based on our existing knowledge of neurotransmitters
human and rat neurotransmission are indeed very similar but behavioural testing is quite limited
here is an overview of the tests
[https://en.wikipedia.org/wiki/Animal_models_of_depression#Antidepressant_screening_tests](https://en.wikipedia.org/wiki/Animal_models_of_depression#Antidepressant_screening_tests)
https://en.wikipedia.org/wiki/Conditioned_place_preference
See less“Curious about our global initiative to create cell type atlases of the mammalian brain?”
I've changed careers from research but still follow neuroscience stuff. I just wanted to congratulate you on such a seminal work, I personally would have used this often throughout my career if it was available to me. Any school worth any salt will use this as a teaching tool. Congratulations!
I’ve changed careers from research but still follow neuroscience stuff. I just wanted to congratulate you on such a seminal work, I personally would have used this often throughout my career if it was available to me. Any school worth any salt will use this as a teaching tool. Congratulations!
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